Human TNF-Luc reporter mouse: A new model to quantify inflammatory responses

Tumour necrosis factor (TNF) is a key cytokine during inflammatory responses and its dysregulation is detrimental in many inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease. Here, we used a bacterial artificial chromosome (BAC) construct that expresses luciferase unde...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Minshawi, Faisal, White, Mike R. H., Muller, Werner, Humphreys, Neil, Jackson, Dean, Campbell, Barry J., Adamson, Antony, Papoutsopoulou, Stamatia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336827/
https://ncbi.nlm.nih.gov/pubmed/30655563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36969-x
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