Polymorphisms in MDM2 and TP53 Genes and Risk of Developing Therapy-Related Myeloid Neoplasms

One of the most severe complications after successful cancer therapy is the development of therapy-related myeloid neoplasms (t-MN). Constitutional genetic variation is likely to impact on t-MN risk. We aimed to evaluate if polymorphisms in the p53 pathway can be useful for predicting t-MN susceptib...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cabezas, Maria, García-Quevedo, Lydia, Alonso, Cintia, Manubens, Marta, Álvarez, Yolanda, Barquinero, Joan Francesc, Ramón y Cajal, Santiago, Ortega, Margarita, Blanco, Adoración, Caballín, María Rosa, Armengol, Gemma
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336808/
https://ncbi.nlm.nih.gov/pubmed/30655613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36931-x
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