Polymorphisms in MDM2 and TP53 Genes and Risk of Developing Therapy-Related Myeloid Neoplasms

One of the most severe complications after successful cancer therapy is the development of therapy-related myeloid neoplasms (t-MN). Constitutional genetic variation is likely to impact on t-MN risk. We aimed to evaluate if polymorphisms in the p53 pathway can be useful for predicting t-MN susceptib...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Cabezas, Maria, García-Quevedo, Lydia, Alonso, Cintia, Manubens, Marta, Álvarez, Yolanda, Barquinero, Joan Francesc, Ramón y Cajal, Santiago, Ortega, Margarita, Blanco, Adoración, Caballín, María Rosa, Armengol, Gemma
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336808/
https://ncbi.nlm.nih.gov/pubmed/30655613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36931-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items