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The impact of cigarette smoke exposure, COPD, or asthma status on ABC transporter gene expression in human airway epithelial cells

ABC transporters are conserved in prokaryotes and eukaryotes, with humans expressing 48 transporters divided into 7 classes (ABCA, ABCB, ABCC, ABCD, ABDE, ABCF, and ABCG). Throughout the human body, ABC transporters regulate cAMP levels, chloride secretion, lipid transport, and anti-oxidant response...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Aguiar, Jennifer A., Tamminga, Andrea, Lobb, Briallen, Huff, Ryan D., Nguyen, Jenny P., Kim, Yechan, Dvorkin-Gheva, Anna, Stampfli, Martin R., Doxey, Andrew C., Hirota, Jeremy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336805/
https://ncbi.nlm.nih.gov/pubmed/30655622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36248-9
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