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Blood-treatment of Lyme borreliae demonstrates the mechanism of CspZ-mediated complement evasion to promote systemic infection in vertebrate hosts.

Lyme disease, caused by the spirochete Borrelia burgdorferi, is the most common vector-borne disease in the US and Europe. The spirochetes are transmitted from mammalian and avian reservoir hosts to humans via ticks. Following tick bites, spirochetes colonize the host skin and then disseminate hemat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Microbiol
Hauptverfasser: Marcinkiewicz, Ashley L., Dupuis, Alan P., Zamba-Campero, Maxime, Nowak, Nancy, Kraiczy, Peter, Ram, Sanjay, Kramer, Laura D., Lin, Yi-Pin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336514/
https://ncbi.nlm.nih.gov/pubmed/30571845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12998
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