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Blood-treatment of Lyme borreliae demonstrates the mechanism of CspZ-mediated complement evasion to promote systemic infection in vertebrate hosts.

Lyme disease, caused by the spirochete Borrelia burgdorferi, is the most common vector-borne disease in the US and Europe. The spirochetes are transmitted from mammalian and avian reservoir hosts to humans via ticks. Following tick bites, spirochetes colonize the host skin and then disseminate hemat...

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Detalhes bibliográficos
Publicado no:Cell Microbiol
Principais autores: Marcinkiewicz, Ashley L., Dupuis, Alan P., Zamba-Campero, Maxime, Nowak, Nancy, Kraiczy, Peter, Ram, Sanjay, Kramer, Laura D., Lin, Yi-Pin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336514/
https://ncbi.nlm.nih.gov/pubmed/30571845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12998
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