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Novel leptin receptor signaling mutants identify location and sex dependent modulation of bone density, adiposity and growth.
Leptin, a hormone primarily produced by adipocytes, contributes to the regulation of bone health by modulating bone density, growth and adiposity. Upon leptin binding, multiple sites of the long form of the leptin receptor (LepRb) are phosphorylated to trigger activation of downstream signaling path...
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| Publicado no: | J Cell Biochem |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6336499/ https://ncbi.nlm.nih.gov/pubmed/30269370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.27726 |
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