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Distinct Roles of Extracellular Domains in the Epstein-Barr Virus-Encoded BILF1 Receptor for Signaling and Major Histocompatibility Complex Class I Downregulation

The Epstein-Barr virus (EBV) BILF1 gene encodes a constitutively active G protein-coupled receptor (GPCR) that downregulates major histocompatibility complex (MHC) class I and induces signaling-dependent tumorigenesis. Different BILF1 homologs display highly conserved extracellular loops (ECLs) incl...

詳細記述

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書誌詳細
出版年:mBio
主要な著者: Fares, Suzan, Spiess, Katja, Olesen, Emma T. B., Zuo, Jianmin, Jackson, Sarah, Kledal, Thomas N., Wills, Mark R., Rosenkilde, Mette M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336419/
https://ncbi.nlm.nih.gov/pubmed/30647152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01707-18
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