Bidirectional Analysis of Cryba4-Crybb1 Nascent Transcription and Nuclear Accumulation of Crybb3 mRNAs in Lens Fibers

PURPOSE: Crystallin gene expression during lens fiber cell differentiation is tightly spatially and temporally regulated. A significant fraction of mammalian genes is transcribed from adjacent promoters in opposite directions (“bidirectional” promoters). It is not known whether two proximal genes lo...

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Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Limi, Saima, Zhao, Yilin, Guo, Peng, Lopez-Jones, Melissa, Zheng, Deyou, Singer, Robert H., Skoultchi, Arthur I., Cvekl, Ales
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2019
Fag:
Biochemistry and Molecular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336207/
https://ncbi.nlm.nih.gov/pubmed/30646012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-25921
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