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Transcriptional burst fraction and size dynamics during lens fiber cell differentiation and detailed insights into the denucleation process

Genes are transcribed in irregular pulses of activity termed transcriptional bursts. Cellular differentiation requires coordinated gene expression; however, it is unknown whether the burst fraction (i.e. the number of active phases of transcription) or size/intensity (the number of RNA molecules pro...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Limi, Saima, Senecal, Adrien, Coleman, Robert, Lopez-Jones, Melissa, Guo, Peng, Polumbo, Christina, Singer, Robert H., Skoultchi, Arthur I., Cvekl, Ales
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109918/
https://ncbi.nlm.nih.gov/pubmed/29959226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001927
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