The Molecular Signature of Megakaryocyte-Erythroid Progenitors Reveals a Role for the Cell Cycle in Fate Specification

Megakaryocytic-erythroid progenitors (MEPs) give rise to the cells that produce red blood cells and platelets. Although the mechanisms underlying megakaryocytic (MK) and erythroid (E) maturation have been described, those controlling their specification from MEPs are unknown. Single-cell RNA sequenc...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Lu, Yi-Chien, Sanada, Chad, Xavier-Ferrucio, Juliana, Wang, Lin, Zhang, Ping-Xia, Leighton Grimes, H., Venkatasubramanian, Meenakshi, Chetal, Kashish, Aronow, Bruce, Salomonis, Nathan, Krause, Diane S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336197/
https://ncbi.nlm.nih.gov/pubmed/30463007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.084
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