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Long non-coding RNA CASC2 upregulates PTEN to suppress pancreatic carcinoma cell metastasis by downregulating miR-21

BACKGROUND: The mechanism of pancreatic cancer metastasis remains poorly understood. Recently, lncRNA CASC2 has been demonstrated to be a tumor suppressor in various types of cancer. This study aimed to explore the mechanism of CASC2 in the regulation of pancreatic cancer metastasis. METHODS: The ex...

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Detalles Bibliográficos
Publicado en:Cancer Cell Int
Main Authors: Zhang, Hui, Feng, Xielin, Zhang, Mingyi, Liu, Aixiang, Tian, Lang, Bo, Wentao, Wang, Haiqing, Hu, Yong
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335738/
https://ncbi.nlm.nih.gov/pubmed/30675129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0728-y
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