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The role of 3D genome organization in disease: from compartments to single nucleotides

Since the advent of the chromosome conformation capture technology, our understanding of the human genome 3D organization has grown rapidly and we now know that human interphase chromosomes are folded into multiple layers of hierarchical structures and each layer can play a critical role in transcri...

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Detalhes bibliográficos
Publicado no:Semin Cell Dev Biol
Main Authors: Chakraborty, Abhijit, Ay, Ferhat
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335187/
https://ncbi.nlm.nih.gov/pubmed/30017907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2018.07.005
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