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Lactic acid accumulation in the tumor microenvironment suppresses (18)F-FDG uptake

The process by which tumor cells take up 18F-fluorodeoxyglucose (FDG) is heterogeneous and influenced by a multitude of factors. In mouse tumor grafts, the core of the tumor often presents lower FDG uptake than the periphery. Whether this pattern is caused by the intrinsic avidity of individual cell...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Türkcan, Silvan, Kiru, Louise, Naczynski, Dominik J., Sasportas, Laura S., Pratx, Guillem
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335173/
https://ncbi.nlm.nih.gov/pubmed/30510121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0492
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