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Lactic acid accumulation in the tumor microenvironment suppresses (18)F-FDG uptake

The process by which tumor cells take up 18F-fluorodeoxyglucose (FDG) is heterogeneous and influenced by a multitude of factors. In mouse tumor grafts, the core of the tumor often presents lower FDG uptake than the periphery. Whether this pattern is caused by the intrinsic avidity of individual cell...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Türkcan, Silvan, Kiru, Louise, Naczynski, Dominik J., Sasportas, Laura S., Pratx, Guillem
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335173/
https://ncbi.nlm.nih.gov/pubmed/30510121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0492
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