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Smad7 Promotes Healing of Radiotherapy-Induced Oral Mucositis without Compromising Oral Cancer Therapy in a Xenograft Mouse Model

PURPOSE: We previously reported preventive and therapeutic effects of Smad7, a multifunctional protein, on radiation-induced mucositis in mice without promoting human oral cancer cell survival or migration in vitro. The current study aims to determine whether a Smad7-based biologic can treat existin...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Luo, Jing Jing, Bian, Li, Blevins, Melanie A., Wang, Donna, Liang, Chao, Du, Danfeng, Wu, Fanglong, Holwerda, Barry, Zhao, Rui, Raben, David, Zhou, Hongmei, Young, Christian D., Wang, Xiao-Jing
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335168/
https://ncbi.nlm.nih.gov/pubmed/30185419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-1081
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