Impaired Tumor Necrosis Factor-α-driven Dendritic Cell Activation Limits Lipopolysaccharide-induced Protection from Allergic Inflammation in Infants.

Infants have higher risk of developing allergic asthma than adults. However, the underlying mechanism remains unknown. We show here that sensitization of mice with house-dust-mite (HDM) in the presence of low-dose lipopolysaccharide (LPS) prevented T helper-2 (Th2) cell-allergic responses in adult b...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Bachus, Holly, Kaur, Kamaljeet, Papillion, Amber M., Marquez-Lago, Tatiana T., Yu, Zhihong, Ballesteros-Tato, André, Matalon, Sadis, León, Beatriz
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335154/
https://ncbi.nlm.nih.gov/pubmed/30635238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.11.012
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