Experimental heat stress nephropathy and liver injury are improved by allopurinol

An epidemic of chronic kidney disease (CKD) has been observed in Central America among workers in the sugarcane fields. One hypothesis is that the CKD may be caused by recurrent heat stress and dehydration, and potentially by hyperuricemia. Accordingly, we developed a murine model of kidney injury a...

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Bibliografski detalji
Izdano u:Am J Physiol Renal Physiol
Glavni autori: Roncal-Jimenez, Carlos A., Sato, Yuka, Milagres, Tamara, Andres Hernando, Ana, García, Gabriela, Bjornstad, Petter, Dawson, Jaime Butler, Sorensen, Cecilia, Newman, Lee, Krisher, Lyndsay, Madero, Magdalena, Glaser, Jason, Gárcía-Trabanino, Ramón, Romero, Emmanuel Jarquin, Song, Zhilin, Jensen, Thomas, Kuwabara, Masanari, Rodriguez-Iturbe, Bernardo, Sanchez-Lozada, Laura Gabriela, Lanaspa, Miguel A., Johnson, Richard J.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335002/
https://ncbi.nlm.nih.gov/pubmed/29667911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00543.2017
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