Experimental heat stress nephropathy and liver injury are improved by allopurinol

An epidemic of chronic kidney disease (CKD) has been observed in Central America among workers in the sugarcane fields. One hypothesis is that the CKD may be caused by recurrent heat stress and dehydration, and potentially by hyperuricemia. Accordingly, we developed a murine model of kidney injury a...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Renal Physiol
Main Authors: Roncal-Jimenez, Carlos A., Sato, Yuka, Milagres, Tamara, Andres Hernando, Ana, García, Gabriela, Bjornstad, Petter, Dawson, Jaime Butler, Sorensen, Cecilia, Newman, Lee, Krisher, Lyndsay, Madero, Magdalena, Glaser, Jason, Gárcía-Trabanino, Ramón, Romero, Emmanuel Jarquin, Song, Zhilin, Jensen, Thomas, Kuwabara, Masanari, Rodriguez-Iturbe, Bernardo, Sanchez-Lozada, Laura Gabriela, Lanaspa, Miguel A., Johnson, Richard J.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335002/
https://ncbi.nlm.nih.gov/pubmed/29667911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00543.2017
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