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Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease
Enhancers function as DNA logic gates and may control specialized functions of billions of neurons. Here we show a tailored program of noncoding genome elements active in situ in physiologically distinct dopamine neurons of the human brain. We found 71,022 transcribed noncoding elements, many of whi...
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Publicado no: | Nat Neurosci |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6334654/ https://ncbi.nlm.nih.gov/pubmed/30224808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0223-0 |
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