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Stereoselective organocatalyzed glycosylations – thiouracil, thioureas and monothiophthalimide act as Brønsted acid catalysts at low loadings

Thiouracil catalyzes stereoselective glycosylations with galactals in loadings as low as 0.1 mol%. It is proposed that in these glycosylations thiouracil, monothiophthalimide, and the previously reported catalyst, Schreiner's thiourea, do not operate via a double H-bonding mechanism but rather...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Bradshaw, G. A., Colgan, A. C., Allen, N. P., Pongener, I., Boland, M. B., Ortin, Y., McGarrigle, E. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334493/
https://ncbi.nlm.nih.gov/pubmed/30713648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc02788a
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