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Iterative Assembly of Macrocyclic Lactones using Successive Ring Expansion Reactions

Macrocyclic lactones can be prepared from lactams and hydroxyacid derivatives via an efficient 3‐ or 4‐atom iterative ring expansion protocol. The products can also be expanded using amino acid‐based linear fragments, meaning that macrocycles with precise sequences of hydroxy‐ and amino acids can be...

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Bibliografiske detaljer
Udgivet i:Chemistry
Main Authors: Stephens, Thomas C., Lawer, Aggie, French, Thomas, Unsworth, William P.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334170/
https://ncbi.nlm.nih.gov/pubmed/30011360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201803064
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