Ginsenosides Act As Positive Modulators of P2X4 Receptors

We investigated the selectivity of protopanaxadiol ginsenosides from Panax ginseng acting as positive allosteric modulators on P2X receptors. ATP-induced responses were measured in stable cell lines overexpressing human P2X4 using a YOPRO-1 dye uptake assay, intracellular calcium measurements, and w...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Dhuna, Kshitija, Felgate, Matthew, Bidula, Stefan M., Walpole, Samuel, Bibic, Lucka, Cromer, Brett A., Angulo, Jesus, Sanderson, Julie, Stebbing, Martin J., Stokes, Leanne
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334005/
https://ncbi.nlm.nih.gov/pubmed/30545933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.118.113696
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