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Optogenetic stimulation of medial prefrontal cortex Drd1 neurons produces rapid and long-lasting antidepressant effects

Impaired function in the medial prefrontal cortex (mPFC) contributes to depression, and the therapeutic response produced by novel rapid-acting antidepressants such as ketamine are mediated by mPFC activity. The mPFC contains multiple types of pyramidal cells, but it is unclear whether a particular...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Hare, Brendan D., Shinohara, Ryota, Liu, Rong Jian, Pothula, Santosh, DiLeone, Ralph J., Duman, Ronald S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333924/
https://ncbi.nlm.nih.gov/pubmed/30644390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08168-9
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