Genome-scale metabolic modeling of responses to polymyxins in Pseudomonas aeruginosa

BACKGROUND: Pseudomonas aeruginosa often causes multidrug-resistant infections in immunocompromised patients, and polymyxins are often used as the last-line therapy. Alarmingly, resistance to polymyxins has been increasingly reported worldwide recently. To rescue this last-resort class of antibiotic...

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Bibliografiske detaljer
Udgivet i:Gigascience
Main Authors: Zhu, Yan, Czauderna, Tobias, Zhao, Jinxin, Klapperstueck, Matthias, Maifiah, Mohd Hafidz Mahamad, Han, Mei-Ling, Lu, Jing, Sommer, Björn, Velkov, Tony, Lithgow, Trevor, Song, Jiangning, Schreiber, Falk, Li, Jian
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333913/
https://ncbi.nlm.nih.gov/pubmed/29688451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giy021
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