Membrane-anchored carbonic anhydrase IV interacts with monocarboxylate transporters via their chaperones CD147 and GP70

Monocarboxylate transporters (MCTs) mediate the proton-coupled exchange of high-energy metabolites, including lactate and pyruvate, between cells and tissues. The transport activity of MCT1, MCT2, and MCT4 can be facilitated by the extracellular carbonic anhydrase IV (CAIV) via a noncatalytic mechan...

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Vydáno v:J Biol Chem
Hlavní autoři: Forero-Quintero, Linda S., Ames, Samantha, Schneider, Hans-Peter, Thyssen, Anne, Boone, Christopher D., Andring, Jacob T., McKenna, Robert, Casey, Joseph R., Deitmer, Joachim W., Becker, Holger M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333884/
https://ncbi.nlm.nih.gov/pubmed/30446621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005536
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