Deregulation and Targeting of TP53 Pathway in Multiple Myeloma

Multiple Myeloma (MM) is an incurable disease characterized by a clonal evolution across the course of the diseases and multiple lines of treatment. Among genomic drivers of the disease, alterations of the tumor suppressor TP53 are associated with poor outcomes. In physiological situation, once acti...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Jovanović, Katarina K., Escure, Guillaume, Demonchy, Jordane, Willaume, Alexandre, Van de Wyngaert, Zoe, Farhat, Meryem, Chauvet, Paul, Facon, Thierry, Quesnel, Bruno, Manier, Salomon
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333636/
https://ncbi.nlm.nih.gov/pubmed/30687640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00665
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