Mutations in TP53 are exclusively associated with del(17p) in multiple myeloma

Deletion of the 17p13 chromosomal region [del(17p)] is associated with a poor outcome in multiple myeloma. Most of the studies have targeted the TP53 gene for deletion analyses, although no study showed that this gene is the deletion target. In order to address this issue, we sequenced the TP53 gene...

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Detalhes bibliográficos
Main Authors: Lodé, Laurence, Eveillard, Marion, Trichet, Valérie, Soussi, Thierry, Wuillème, Soraya, Richebourg, Steven, Magrangeas, Florence, Ifrah, Norbert, Campion, Loïc, Traullé, Catherine, Guilhot, François, Caillot, Denis, Marit, Gérald, Mathiot, Claire, Facon, Thierry, Attal, Michel, Harousseau, Jean-Luc, Moreau, Philippe, Minvielle, Stéphane, Avet-Loiseau, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2010
Assuntos:
Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966923/
https://ncbi.nlm.nih.gov/pubmed/20634494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.023697
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