MTOR-independent autophagy induced by interrupted endoplasmic reticulum-mitochondrial Ca(2+) communication: a dead end in cancer cells

The interruption of endoplasmic reticulum (ER)-mitochondrial Ca(2+) communication induces a bioenergetic crisis characterized by an increase of MTOR-independent AMPK-dependent macroautophagic/autophagic flux, which is not sufficient to reestablish the metabolic and energetic homeostasis in cancer ce...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Ahumada-Castro, Ulises, Silva-Pavez, Eduardo, Lovy, Alenka, Pardo, Evelyn, Molgό, Jordi, Cárdenas, César
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Commentary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333456/
https://ncbi.nlm.nih.gov/pubmed/30351219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1537769
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