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Deep learning identifies genome-wide DNA binding sites of long noncoding RNAs

Long noncoding RNAs (lncRNAs) can exert their function by interacting with the DNA via triplex structure formation. Even though this has been validated with a handful of experiments, a genome-wide analysis of lncRNA-DNA binding is needed. In this paper, we develop and interpret deep learning models...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Wang, Fan, Chainani, Pranik, White, Tommy, Yang, Jin, Liu, Yu, Soibam, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333433/
https://ncbi.nlm.nih.gov/pubmed/30486737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1551704
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