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The long noncoding RNAs NEAT1 and MALAT1 bind active chromatin sites

Mechanistic roles for many lncRNAs are poorly understood in part because their direct interactions with genomic loci and proteins are difficult to assess. Using a method to purify endogenous RNAs and their associated factors, we mapped the genomic binding sites for two highly expressed human lncRNAs...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: West, Jason A., Davis, Christopher P., Sunwoo, Hongjae, Simon, Matthew D., Sadreyev, Ruslan I., Wang, Peggy I., Tolstorukov, Michael Y., Kingston, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428586/
https://ncbi.nlm.nih.gov/pubmed/25155612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.07.012
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