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Improvement of the CRISPR-Cpf1 system with ribozyme-processed crRNA

The recently discovered clustered regularly interspaced short palindromic repeats (CRISPR)-Cpf1 system expands the genome editing toolbox. This system exhibits several distinct features compared to the widely used CRISPR-Cas9 system, but has reduced gene editing efficiency. To optimize the CRISPR-Cp...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Gao, Zongliang, Herrera-Carrillo, Elena, Berkhout, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333430/
https://ncbi.nlm.nih.gov/pubmed/30470168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1551703
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