Effect of Imatinib on Bone Marrow Morphology and Angiogenesis in Chronic Myeloid Leukemia

BACKGROUND AND OBJECTIVES: Chronic myeloid leukemia (CML) is characterized by hyperproliferation of myeloid precursors, increased fibrosis, and neoangiogenesis in the bone marrow. Imatinib inhibits BCR-ABL tyrosine kinase produced due to reciprocal translocation t(9;22) in neoplastic CML cells. It r...

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Detalhes bibliográficos
Publicado no:Adv Hematol
Main Authors: Pandey, Neetu, Yadav, Geeta, Kushwaha, Rashmi, Verma, Shailendra Prasad, Singh, Uma Shankar, Kumar, Ashutosh, Mishra, Prabhaker
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6332991/
https://ncbi.nlm.nih.gov/pubmed/30713559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1835091
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