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Complete Disaggregation of MCF-7-derived Breast Tumour Spheroids with Very Low Concentrations of α-Mangostin Loaded in CD44 Thioaptamer-tagged Nanoparticles

Background: α-Mangostin (αMG) is a natural substance that exerts a wide range of antitumor effects. Recently, we described that free αMG was able to dissociate multicellular tumour spheroids (MCTSs) generated from breast carcinoma cells and to reduce their cellular viability and motility. Here, αMG...

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Detalhes bibliográficos
Publicado no:Int J Med Sci
Main Authors: Bonafè, Francesca, Pazzini, Claudia, Marchionni, Silvia, Guarnieri, Carlo, Muscari, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6332479/
https://ncbi.nlm.nih.gov/pubmed/30662326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.28135
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