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Combinatorial selection of DNA thioaptamers targeted towards the HA binding domain of human CD44

CD44, the primary receptor for hyaluronic acid, plays an important role in tumor growth and metastasis. CD44-hyaluronic acid interactions can be exploited for targeted delivery of anti-cancer agents specifically to cancer cells. Although various splicing variants of CD44 are expressed on the plasma...

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Detalhes bibliográficos
Main Authors: Somasunderam, Anoma, Thiviyanathan, Varatharasa, Tanaka, Takemi, Li, Xin, Neerathilingam, Muniasamy, Lokesh, Ganesh Lakshmana Rao, Mann, Aman, Peng, Yang, Ferrari, Mauro, Klostergaard, Jim, Gorenstein, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981344/
https://ncbi.nlm.nih.gov/pubmed/20843027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1009503
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