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Combinatorial selection of DNA thioaptamers targeted towards the HA binding domain of human CD44
CD44, the primary receptor for hyaluronic acid, plays an important role in tumor growth and metastasis. CD44-hyaluronic acid interactions can be exploited for targeted delivery of anti-cancer agents specifically to cancer cells. Although various splicing variants of CD44 are expressed on the plasma...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2981344/ https://ncbi.nlm.nih.gov/pubmed/20843027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1009503 |
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