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Thioaptamers Targeting Dengue Virus Type-2 Envelope Protein Domain III

Thioaptamers targeting the dengue-2 virus (DENV-2) envelope protein domain III (EDIII) were developed. EDIII, which contains epitopes for binding neutralizing antibodies, is the putative host-receptor binding domain and is thus an attractive target for development of vaccines, anti-viral therapeutic...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Gandham, Sai Hari A., Volk, David E., Rao, Lokesh G. L., Neerathilingam, Muniasamy, Gorenstein, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272640/
https://ncbi.nlm.nih.gov/pubmed/25261724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.09.053
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