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Role of Polymeric Excipients in the Stabilization of Olanzapine when Exposed to Aqueous Environments

Hydrate formation is a phase transition which can occur during manufacturing processes involving water. This work considers the prevention of hydration of anhydrous olanzapine and hydrate conversions in the presence of water and polymers (polyethyleneglycol; hydroxypropylcellulose; polyvinylpyrrolid...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Paisana, Maria, Wahl, Martin, Pinto, João
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6332009/
https://ncbi.nlm.nih.gov/pubmed/26703534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules201219832
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