Chemotherapeutic agent 5-fluorouracil increases survival of SOD1 mouse model of ALS

Amyotrophic lateral sclerosis (ALS) is a lethal motor neuron disease with no cure. Currently there are only two ALS drugs approved by the FDA, both with a limited therapeutic effect. In the search for drug candidates for ALS, we studied the effect of known stem cell mobilizing agents (treatment) and...

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Опубликовано в: :PLoS One
Главные авторы: Rando, Amaya, de la Torre, Miriam, Martinez-Muriana, Anna, Zaragoza, Pilar, Musaro, Antonio, Hernández, Sara, Navarro, Xavier, Toivonen, Janne M., Osta, Rosario
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331125/
https://ncbi.nlm.nih.gov/pubmed/30640943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210752
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