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Mechanistic investigation into the C(sp(3))–H acetoxylation of morpholinones

The study of a selective palladium(ii)-catalyzed C(sp(3))–H acetoxylation reaction on a class of cyclic alkyl amines is reported. Computational modelling and kinetic studies were used to provide support for a mechanism involving selective C–O bond formation from a γ-aminoalkyl-Pd(iv) intermediate. T...

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Publicat a:Chem Sci
Autors principals: Buettner, Cornelia S., Willcox, Darren, Chappell, Ben. G. N., Gaunt, Matthew J.
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331033/
https://ncbi.nlm.nih.gov/pubmed/30713620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc03434f
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