A two gene-based risk score predicts alcoholic cirrhosis development in males with at-risk alcohol consumption

BACKGROUND: Alcoholic cirrhosis represents 1% of all cause-of-deaths worldwide. Its incidence is higher in males and results from the combination of environmental and genetic factors. Among all the genetic determinants of alcoholic cirrhosis, the patatin-like phospholipase domain protein 3 (PNPLA3)...

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Dettagli Bibliografici
Pubblicato in:Appl Clin Genet
Autori principali: Mancina, Rosellina Margherita, Ferri, Flaminia, Farcomeni, Alessio, Molinaro, Antonio, Maffongelli, Angela, Mischitelli, Monica, Poli, Edoardo, Parlati, Lucia, Burza, Maria Antonella, De Santis, Adriano, Attilia, Fabio, Rotondo, Claudia, Rando, Maria Margherita, Attilia, Maria Luisa, Ceccanti, Mauro, Ginanni Corradini, Stefano
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2019
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330982/
https://ncbi.nlm.nih.gov/pubmed/30666147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S187922
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