A two gene-based risk score predicts alcoholic cirrhosis development in males with at-risk alcohol consumption

BACKGROUND: Alcoholic cirrhosis represents 1% of all cause-of-deaths worldwide. Its incidence is higher in males and results from the combination of environmental and genetic factors. Among all the genetic determinants of alcoholic cirrhosis, the patatin-like phospholipase domain protein 3 (PNPLA3)...

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Detalhes bibliográficos
Publicado no:Appl Clin Genet
Main Authors: Mancina, Rosellina Margherita, Ferri, Flaminia, Farcomeni, Alessio, Molinaro, Antonio, Maffongelli, Angela, Mischitelli, Monica, Poli, Edoardo, Parlati, Lucia, Burza, Maria Antonella, De Santis, Adriano, Attilia, Fabio, Rotondo, Claudia, Rando, Maria Margherita, Attilia, Maria Luisa, Ceccanti, Mauro, Ginanni Corradini, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330982/
https://ncbi.nlm.nih.gov/pubmed/30666147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S187922
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