A two gene-based risk score predicts alcoholic cirrhosis development in males with at-risk alcohol consumption

BACKGROUND: Alcoholic cirrhosis represents 1% of all cause-of-deaths worldwide. Its incidence is higher in males and results from the combination of environmental and genetic factors. Among all the genetic determinants of alcoholic cirrhosis, the patatin-like phospholipase domain protein 3 (PNPLA3)...

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Dades bibliogràfiques
Publicat a:Appl Clin Genet
Autors principals: Mancina, Rosellina Margherita, Ferri, Flaminia, Farcomeni, Alessio, Molinaro, Antonio, Maffongelli, Angela, Mischitelli, Monica, Poli, Edoardo, Parlati, Lucia, Burza, Maria Antonella, De Santis, Adriano, Attilia, Fabio, Rotondo, Claudia, Rando, Maria Margherita, Attilia, Maria Luisa, Ceccanti, Mauro, Ginanni Corradini, Stefano
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330982/
https://ncbi.nlm.nih.gov/pubmed/30666147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S187922
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