Antigenic “Hot- Spots” on the TSH Receptor Hinge Region

The TSH receptor (TSHR) hinge region was previously considered an inert scaffold connecting the leucine-rich ectodomain to the transmembrane region of the receptor. However, mutation studies have established the hinge region to be an extended hormone-binding site in addition to containing a region w...

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Bibliographic Details
Published in:Front Endocrinol (Lausanne)
Main Authors: Sun, Simeng, Summachiwakij, Sarawut, Schneck, Ora, Morshed, Syed A., Ma, Risheng, Latif, Rauf, Davies, Terry F.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Endocrinology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330735/
https://ncbi.nlm.nih.gov/pubmed/30666231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00765
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