Glucagon-like peptide-1 (GLP-1) mediates the protective effects of dipeptidyl peptidase IV inhibition on pulmonary hypertension

BACKGROUND: Pulmonary hypertension (PH) is a progressive disease leading to death ultimately. Our recently published data demonstrated that inhibiting dipeptidyl peptidase IV (DPP-4) alleviated pulmonary vascular remodeling in experimental PH. However, whether glucagon-like peptide-1 (GLP-1) mediate...

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Bibliographische Detailangaben
Veröffentlicht in:J Biomed Sci
Hauptverfasser: Wang, Jingjing, Yu, Min, Xu, Jian, Cheng, Yusheng, Li, Xiang, Wei, Guihong, Wang, Hong, Kong, Hui, Xie, Weiping
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330403/
https://ncbi.nlm.nih.gov/pubmed/30634956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-019-0496-y
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