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Dipeptidyl peptidase IV inhibitors in diabetes: more than inhibition of glucagon-like peptide-1 metabolism?

Inhibitors of the protease dipeptidyl peptidase IV (DPP-IV) are promising new drugs for the treatment of type 2 diabetes. They are thought to act by inhibiting the breakdown of glucagon-like peptide-1 and, thereby, selectively enhancing insulin release under conditions when it is physiologically req...

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Hlavní autoři: Michel, Martin C., Fliers, Eric, Van Noorden, Cornelis J. F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323035/
https://ncbi.nlm.nih.gov/pubmed/18398599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-008-0280-0
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