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SLIMEr: probing flexibility of lipid metabolism in yeast with an improved constraint-based modeling framework

BACKGROUND: A recurrent problem in genome-scale metabolic models (GEMs) is to correctly represent lipids as biomass requirements, due to the numerous of possible combinations of individual lipid species and the corresponding lack of fully detailed data. In this study we present SLIMEr, a formalism f...

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Veröffentlicht in:BMC Syst Biol
Hauptverfasser: Sánchez, Benjamín J., Li, Feiran, Kerkhoven, Eduard J., Nielsen, Jens
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330394/
https://ncbi.nlm.nih.gov/pubmed/30634957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-018-0673-8
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