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SLIMEr: probing flexibility of lipid metabolism in yeast with an improved constraint-based modeling framework

BACKGROUND: A recurrent problem in genome-scale metabolic models (GEMs) is to correctly represent lipids as biomass requirements, due to the numerous of possible combinations of individual lipid species and the corresponding lack of fully detailed data. In this study we present SLIMEr, a formalism f...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Sánchez, Benjamín J., Li, Feiran, Kerkhoven, Eduard J., Nielsen, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330394/
https://ncbi.nlm.nih.gov/pubmed/30634957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-018-0673-8
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