Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies

Heavy chain-only antibodies (HCAbs) do not associate with light chains and their V(H) regions are functional as single domains, forming the smallest active antibody fragment. These V(H) regions are ideal building blocks for a variety of antibody-based biologics because they tolerate fusion to other...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Clarke, Starlynn C., Ma, Biao, Trinklein, Nathan D., Schellenberger, Ute, Osborn, Michael J., Ouisse, Laure-Hélène, Boudreau, Andrew, Davison, Laura M., Harris, Katherine E., Ugamraj, Harshad S., Balasubramani, Aarti, Dang, Kevin H., Jorgensen, Brett, Ogana, Heather Anne N., Pham, Duy T., Pratap, Payal P., Sankaran, Preethi, Anegon, Ignacio, van Schooten, Wim C., Brüggemann, Marianne, Buelow, Roland, Force Aldred, Shelley
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330309/
https://ncbi.nlm.nih.gov/pubmed/30666250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03037
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados