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Making ends meet: Targeted integration of DNA fragments by genome editing

Targeted insertion of large pieces of DNA is an important goal of genetic engineering. However, this goal has been elusive since classical methods for homology-directed repair are inefficient and often not feasible in many systems. Recent advances are described here that enable site-specific genomic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Chromosoma
Prif Awduron: Yamamoto, Yutaka, Gerbi, Susan A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330168/
https://ncbi.nlm.nih.gov/pubmed/30003320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-018-0677-6
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