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Making ends meet: Targeted integration of DNA fragments by genome editing

Targeted insertion of large pieces of DNA is an important goal of genetic engineering. However, this goal has been elusive since classical methods for homology-directed repair are inefficient and often not feasible in many systems. Recent advances are described here that enable site-specific genomic...

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Detalhes bibliográficos
Publicado no:Chromosoma
Main Authors: Yamamoto, Yutaka, Gerbi, Susan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330168/
https://ncbi.nlm.nih.gov/pubmed/30003320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-018-0677-6
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