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Old Trade, New Tricks: Insights into the Spontaneous Mutation Process from the Partnering of Classical Mutation Accumulation Experiments with High-Throughput Genomic Approaches

Mutations spawn genetic variation which, in turn, fuels evolution. Hence, experimental investigations into the rate and fitness effects of spontaneous mutations are central to the study of evolution. Mutation accumulation (MA) experiments have served as a cornerstone for furthering our understanding...

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Detalhes bibliográficos
Publicado no:Genome Biol Evol
Main Authors: Katju, Vaishali, Bergthorsson, Ulfar
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330053/
https://ncbi.nlm.nih.gov/pubmed/30476040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evy252
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