Semaphorin signaling via MICAL3 induces symmetric cell division to expand breast cancer stem-like cells

Cancer stem-like cells (CSCs) are expanded in the CSC niche by increased frequency of symmetric cell divisions at the expense of asymmetric cell divisions. The symmetric division of CSCs is important for the malignant properties of cancer; however, underlying molecular mechanisms remain largely elus...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tominaga, Kana, Minato, Hiroshi, Murayama, Takahiko, Sasahara, Asako, Nishimura, Tatsunori, Kiyokawa, Etsuko, Kanauchi, Hajime, Shimizu, Seiichiro, Sato, Ayaka, Nishioka, Kotoe, Tsuji, Ei-ichi, Yano, Masao, Ogawa, Toshihisa, Ishii, Hideshi, Mori, Masaki, Akashi, Koichi, Okamoto, Koji, Tanabe, Masahiko, Tada, Kei-ichiro, Tojo, Arinobu, Gotoh, Noriko
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329980/
https://ncbi.nlm.nih.gov/pubmed/30587593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806851116
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